Evidence and interdisciplinary consensus-based German guidelines: surgical treatment and radiotherapy of melanoma

• DOI: 10.1097/cmr.0b013e3282f0c893
• Publication Date: 2009-03-05T13:00:15Z
• Authors: Claus Garbe; Axel Hauschild; Matthias Volkenandt; Dirk Schadendorf; Wilhelm Stolz; Uwe Reinhold; Rolf-Dieter Kortmann; Christoph Kettelhack; Bernhard Frerich; Ulrich Keilholz; Reinhard Dummer; Günther Sebastian; Wolfgang Tilgen; Gerold Schuler; Andreas Mackensen; Roland Kaufmann
• Keywords: Primary tumor

The primary treatment of a melanoma is surgical excision. An excisional biopsy preferred, and safety margins 1 cm for tumor thickness up to 2 mm higher should be applied either at excision or in two-step procedure. When dealing with facial, acral anogenital melanomas, micrographic control the may preferable allow reduced conservation tissue. sentinel lymph node performed patients whose thicker than 1.0 this operation centers where both operative nuclear medicine teams are experienced. In clinically identified metastases, radical dissection considered standard therapy. If distant metastases involve just one internal organ removal feasible, then surgery seen as therapy choice. Radiation indicated only those cases which impossible not reasonable. regional nodes, radiation usually recommended when complete (R1 resection) if nodes inoperable. particularly bone brain soft tissue metastases.