Age and gender related patterns in carotid-femoral PWV and carotid and femoral stiffness in a large healthy, middle-aged population

• DOI: 10.1097/hjh.0b013e3282ffac00
• Publication Date: 2008-06-09T07:12:50Z
• Authors: Sebastian J Verme...; Ernst R Rietzschel; Marc L De Buyzere; Dirk De Bacquer; Guy De Backer; Luc M Van Bortel; Thierry C Gillebert; Pascal R Verdonck; Patrick Segers
• Keywords: Adult; Male; Age Factors; Middle Aged; Elasticity; Biomechanical Phenomena; Femoral Artery; 03 medical and health sciences; Carotid Arteries; Sex Factors; 0302 clinical medicine; Belgium; Humans; Female; Aorta; Blood Flow Velocity; Compliance

The relationship between aortic (carotid-femoral) pulse wave velocity and stiffness measures based on local diameter pressure readings is not yet fully understood.We compared the with age gender of to indices (compliance distensibility coefficient) evaluated at common carotid femoral arteries in 2195 (1131 women) apparently healthy subjects, aged 35-55 years participating Asklepios study. Aortic was further previously reported central arterial parameters same population. Subjects were divided into four groups for analysis.Femoral higher men than women (P < 0.001) but did change no age-gender interaction evident. Carotid increased showed a significant interaction, increasing more rapidly men, crossing over around 45. differ women, increase 0.001). No evident.The relation range women. Depending parameter used, effects evident artery are or found centrally. Though relevance these differences requires evaluation longitudinal study outcome data, they need be kept mind when designing interpreting results from studies.