Performance of a Novel Dual-Electrode Bipolar Radiofrequency Ablation Device a Chronic Porcine Study

• DOI: 10.1097/imi.0b013e31820bc57f
• Publication Date: 2011-02-16T10:46:15Z
• Authors: Rochus K. Voeller; Andreas Zierer; Richard B. Schues...; Ralph J. Damiano
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

: Over recent years, a variety of energy sources, including bipolar radiofrequency, have been used to replace the traditional incisions Cox-Maze procedure for surgical treatment atrial fibrillation (AF). The purpose this study was evaluate safety and efficacy novel dual-electrode radiofrequency ablation device Synergy (Atricure, Inc., Cincinnati, OH USA) AF in chronic porcine model.: Six domestic pigs underwent modified IV without cardiopulmonary bypass using device. Animals survived 30 days. Each pig then induction killed remove heart en bloc histologic assessment. line dissected perpendicularly at 5-mm intervals assess lesion width, depth, transmurality.: All animals operation. Electrical isolation left appendage pulmonary veins were documented by pacing acutely days after operation all six animals. failed be induced There no gross evidence intra-atrial thrombus formation or stricture veins. ablations (n = 209) examined discrete, linear, transmural, with mean width 3.0 ± 0.7 mm depth 5.4 3.3 mm. time 16.3 4.4 seconds, total delivery 238 170 J.: Atricure able create reliable transmural lesions on beating bypass. lines significantly wider when compared its predecessor, Isolator II.