CONGENITAL CYTOMEGALOVIRUS INFECTION IN A HIGHLY SEROPOSITIVE SEMI-URBAN POPULATION IN INDIA

• DOI: 10.1097/inf.0b013e3181723d55
• Publication Date: 2008-08-28T04:02:28Z
• Authors: Lalit Dar; Sunil Kumar Pati; A Raj Kumar Patro; Ashok Kumar Deorari; Sanjay Rai; Shashi Kant; Shobha Broor; Karen B. Fowler; William J. Britt; Suresh B. Boppana
• Keywords: Adult; Rural Population; Adolescent; Incidence; Infant, Newborn; Cytomegalovirus; India; Mothers; Urine; Antibodies, Viral; Infant, Newborn, Diseases; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Immunoglobulin M; Cytomegalovirus Infections; Splenomegaly; Humans; Female; Prospective Studies; Hearing Loss; Hepatomegaly

To determine the incidence and natural history of congenital cytomegalovirus (CMV) infection in a population of women with near universal serologic reactivity for CMV, a prospective study of 423 women attending the antenatal clinic of the Comprehensive Rural Health Center in northern India was conducted. All 9 (2.1%) CMV positive infants were born to mothers who were CMV seropositive at the first antenatal visit. One child had hepatosplenomegaly at birth and another child had mild unilateral hearing loss at 4 months of age.