TRENDS IN HOSPITALIZATIONS FROM ALL-CAUSE GASTROENTERITIS IN CHILDREN YOUNGER THAN 5 YEARS OF AGE IN BRAZIL BEFORE AND AFTER HUMAN ROTAVIRUS VACCINE INTRODUCTION, 1998–2007

• DOI: 10.1097/inf.0b013e3181da8f23
• Publication Date: 2010-03-18T09:38:32Z
• Authors: Tatiana Miranda L...; Iolanda Costa; Fakrudeen A. Shafi; Maria Helena Cunha; Eduardo Ortega-Ba...; Alexandre C. Linh...; Romulo E. Colindres
• Keywords: Geography; Infant, Newborn; Rotavirus Vaccines; Infant; Gastroenteritis; 3. Good health; Hospitalization; 03 medical and health sciences; 0302 clinical medicine; Child, Preschool; Humans; Brazil

Rotavirus vaccination was introduced in Brazil in March 2006. We describe trends in hospitalizations from all-cause gastroenteritis in children younger than 5 years during pre- and postvaccination periods using hospital discharge data from Brazil Hospital Information System (SIH-SUS). A reduction in gastroenteritis hospitalizations of 26% and 48% in 2006 and in 2007, respectively, was observed among children younger than 1 year compared with prevaccination period (1998-2005). The largest reduction rates among children younger than 1 year were noted in the South and Southeast regions, approximately 56% in 2007, where vaccine coverage was the highest.