Association of 2009 Pandemic Influenza A (H1N1) Infection and Increased Hospitalization With Parapneumonic Empyema in Children in Utah

• DOI: 10.1097/inf.0b013e3181df2c70
• Publication Date: 2010-04-20T06:47:47Z
• Authors: Krow Ampofo; Amy Herbener; Anne J. Blaschke; Caroline Heyrend; Mark Poritz; Kent Korgenski; Robert Rolfs; Seema Jain; Maria da Glória C...; Fabiana C. Pimenta; Judy Daly; Edward O. Mason; Carrie L. Byington; Andrew T. Pavia
• Keywords: Pandemic; Bacterial pneumonia

Background: During previous influenza pandemics, many deaths were associated with secondary bacterial infection. In April 2009, a previously unknown 2009 A virus (2009 H1N1) emerged, causing global pandemic. We examined the relationship between circulating H1N1 and occurrence of parapneumonic empyema in children. Methods: Children hospitalized from August 2004 to July including period when circulated Utah, identified using International Classification Diseases, Ninth Revision codes. compared average number children diagnosed admissions for per month 4 seasons rates during outbreak. causative bacteria culture polymerase chain reaction (PCR). Results: observed an increase hospitalization pneumonia complicated by severe outbreak spring summer historical data seasons. Streptococcus pneumoniae pyogenes predominant identified. Conclusions: Similar infection S. There is urgent need better understand complications pandemic influenza. interim, vaccines, antiviral agents, pneumococcal vaccines should be used prevent cases whenever possible.