Impact of Universal Pneumococcal Vaccination on Hospitalizations for Pneumonia and Meningitis in Children in Montevideo, Uruguay

• DOI: 10.1097/inf.0b013e3182152bf1
• Publication Date: 2011-03-16T07:17:21Z
• Authors: María Catalina Pírez; Gabriela Algorta; Alejandra Cedrés; Helena Sobrero; Adriana Varela; Gustavo Giachetto; Alicia Montano
• Keywords: Pneumococcal Conjugate Vaccine; Pneumococcal vaccination; Vaccination schedule; Pneumococcal vaccine

In March 2008, Uruguay included PCV7 into the routine vaccination program, in a 2 + 1 schedule for children <2 years of age. Catch-up immunization was offered to born 2007. Greater than 95% received their first and second doses. The aim this study assess effect strategy.Annual hospitalization rates (per 10,000 discharges) community-acquired pneumonia (CAP) <14 age pneumococcal meningitis are described prior (2005-2007), during year implementation (2008) following vaccine introduction (2009). Data regarding age, diagnosis, status, serotype were obtained from Hospital Pereira Rossell databases records.Comparison CAP pneumococcal-CAP (P-CAP) between prevaccine (2005-2007) after (2009) decreased significantly all by 56% 48.2%, respectively. Significant reduction observed P-CAP (serotype 14 26.6 2.5 per A significant 59% seen group; median prevaccination 17 (12.2-24.9) 7 (3-11.8) administration vaccine. No failures or fully immunized children.One Uruguay, there rapid CAP, P-CAP,