Small Risk of Osteoarticular Infections in Children With Asymptomatic Oropharyngeal Carriage of Kingella Kingae

• DOI: 10.1097/inf.0b013e31825d3419
• Publication Date: 2012-05-09T08:19:03Z
• Authors: Dimitri Ceroni; Victor Dubois-Fer...; Rebecca Anderson; Christophe Combes...; Léopold Lamah; Abdessalam Cherkaoui; Jacques Schrenzel
• Keywords: Oropharynx/microbiology; Neisseriaceae Infections; Oropharynx; Kingella kingae; Kingella kingae/genetics/isolation & purification; Polymerase Chain Reaction; Carrier State/epidemiology/microbiology; 03 medical and health sciences; Switzerland/epidemiology; 0302 clinical medicine; info:eu-repo/classification/ddc/616; info:eu-repo/classification/ddc/618; Humans; Prospective Studies; Bone Diseases, Infectious/epidemiology/microbiology; ddc:616; ddc:618; Infant; Neisseriaceae Infections/epidemiology/microbiology; Bone Diseases, Infectious; 3. Good health; Child, Preschool; Carrier State; Switzerland

The aim of this study was to evaluate the absolute risk for children younger than 4 years of age with asymptomatic oropharyngeal carriage of Kingella kingae to sustain an osteoarticular infection. The rate of K. kingae carriage in the oropharyngeal mucosa was 9% among healthy children, and the risk for an asymptomatic carrier to develop an osteoarticular infection due to K. Kingae was estimated to be lower than 1%.