Interferon Gamma–induced Protein-10 Concentrations in Children With Previous Tuberculosis Infections and Disease

• DOI: 10.1097/inf.0b013e3182611152
• Publication Date: 2012-05-31T07:13:30Z
• Authors: Smiti Bihari; Nara Cavalcanti; Jailson B. Correia; Gerlane Alves; Edvaldo Souza; Bernard J. Brabin; Luis E. Cuevas
• Keywords: Adult; Male; Time Factors; Adolescent; Infant; 3. Good health; Chemokine CXCL10; 03 medical and health sciences; Cross-Sectional Studies; 0302 clinical medicine; Child, Preschool; Humans; Tuberculosis; Female; Child; Biomarkers

Interferon gamma-induced protein-10 is a diagnostic test for tuberculosis infection. There is no information on its concentrations over time. Interferon gamma-induced protein-10 was evaluated in 72 children formerly treated or in former contact with tuberculosis using Quantiferon Gold in-tube. Cases and contacts had similar interferon gamma-induced protein-10 concentrations. Concentrations varied with the tuberculin and interferon gamma release tests' concordance or discordance, and were independent of time.