Evaluation of Methods to Determine Excessive Decline of Forced Expiratory Volume in One Second in Workers Exposed to Diacetyl-Containing Flavorings

• DOI: 10.1097/jom.0b013e3181f84577
• Publication Date: 2010-11-11T07:13:29Z
• Authors: Neal F. Chaisson; Kathleen Kreiss; Eva Hnizdo; Artak Hakobyan; Paul L. Enright
• Keywords: Diacetyl; Longitudinal Study

Objective: To evaluate methods for determining excessive short-term decline in forced expiratory volume one second (FEV1) diacetyl-exposed workers. Methods: We evaluated five of longitudinal FEV1 workers and from a comparative cohort: American Thoracic Society (ATS), ACOEM an 8% limit, relative absolute limit on the basis spirometry data variability. Relative risk incidence excess were evaluated. Results: Incidence was 1% cohort using ATS criteria, 4.1% decline, 4.4% with 5.6% by limit. abnormal elevated all methods. Conclusion: Alternative respiratory surveillance may be preferable to or ACOEM.