Serum adiponectin and leptin as predictors of the presence and degree of coronary atherosclerosis

• DOI: 10.1097/mca.0b013e3283452431
• Publication Date: 2011-03-05T08:47:32Z
• Authors: Hosam Hasan-Ali; Nashwa A. Abd El-...; Hosny B. Hamed; Alaa Abd-Elsayed
• Keywords: Coronary atherosclerosis; Degree (music)

The association of adipocyte-derived proteins, adiponectin and leptin, with the degree coronary atherosclerosis has not been well elucidated. This study aimed to determine relationship between serum leptin presence atherosclerosis.Seventy patients 20 matched controls were recruited. Angiographic evaluation was carried out by assessing three atherosclerotic indices, severity (transverse disease), extent (longitudinal pattern (lesion complexity).The independent predictors larger waist/hip ratio, followed higher low-density lipoprotein-cholesterol, low level, older age, current unstable angina, finally previous myocardial infarction (MI). model is a good one as indicated model-adjusted r (50%). For index, lower level far most important predictor, MI, whereas only univariate predictor. 65%. fasting blood glucose level. 62%.Both might play an pathogenic role in occurrence but also severity, extent, lesion complexity artery disease patients.