Multi-b value diffusion-weighted magnetic resonance imaging and intravoxel incoherent motion modeling

• DOI: 10.1097/md.0000000000014459
• Publication Date: 2019-02-07T08:56:52Z
• Authors: Cheng-cheng Liao; Yun-ying Qin; Qi Tang; Xiao-hong Tan; Qing Ke; Yan Rong; Jian-Hong Zhong; Le-qun Li; Hong Cen
• Keywords: Intravoxel incoherent motion; Cut-off

Abstract The diagnostic efficiency of diffusion-weighted magnetic resonance imaging with different b -values and application an intravoxel incoherent motion (IVIM) model for differentiating disease states lymphoma was investigated. Thirty-six patients at initial diagnosis 69 after chemotherapy underwent (DW-MRI) multiple -values. Analysis parameters included the apparent diffusion coefficient (ADC) each -value. Standard ADC, D , ∗, f were calculated using IVIM model. For diagnosis, compared aggressive lymphomas, benign lymph nodes exhibited higher mean ADC (2.34 vs 0.66 × 10 −3 mm 2 /s, P < .01) = 200 s/mm . AUC, sensitivity, specificity, cutoff value 0.992, 96%, 100%, 1.09 ×10 respectively. who had finished chemotherapy, those partial remission (PR) than complete (CR) (56.22 21.81%, .01). 0.937, 94%, 82%, 42.10%, values are most helpful characterizing malignant lymphomas. -value is valuable in identification residual lesions lymphomas chemotherapy.