De-novo nonalcoholic fatty liver disease at 5 years after liver transplantation: prevalence and predictive factors
Steatosis
DOI:
10.1097/meg.0000000000001736
Publication Date:
2020-04-22T01:29:13Z
AUTHORS (9)
ABSTRACT
Background and aims: Nonalcoholic fatty liver disease (NAFLD) is a long-term complication after transplantation. Our aims were to determine de-novo-NAFLD at 5-year post-liver transplantation identify predictive risk factors. Methods: This was retrospective analysis of NAFLD defined as the radiological evidence steatosis. Data from transplanted patients between November 2001 May 2014 collected. Noninvasive fibrosis scores calculated. Predictors de-novo survival assessed by multivariate analyses Kaplan–Meier method. Results: A total 252 transplantations evaluated applying exclusion criteria, (78.6% men) with 54.9 years old (SD ± 9.5). Prevalence 36.1%. Cardiovascular events presented in 19.88% 23.08% non-NAFLD patients, ( P = 0.58). On analysis, male sex (OR, 5.40; 0.001), obesity 3.72; 0.017), metabolic syndrome 4.69; < 0.001) diabetes 2.79; 0.018), predictive. Significant (≥F2) 58–86%. The mean control group 166.3 173.6 months, respectively 0 0.50). Conclusion: De-novo fifth-year frequently associated cardiovascular comorbidity. Male sex, obesity, factors NAFLD. significant proportion had advanced fibrosis. trends toward worse patients’ survival.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (27)
CITATIONS (8)
EXTERNAL LINKS
PlumX Metrics
RECOMMENDATIONS
FAIR ASSESSMENT
Coming soon ....
JUPYTER LAB
Coming soon ....