Clinical impact of fluorodeoxyglucose-positron emission tomography scan/computed tomography in comparison with computed tomography on the detection of colorectal cancer recurrence

• DOI: 10.1097/meg.0b013e328343eaa0
• Publication Date: 2011-02-08T06:04:49Z
• Authors: Céline Deleau; Bruno Buecher; Caroline Rousseau; Françoise Kraeber...; Mathurin Flamant; Stanislas Bruley ...; Eric Frampas; Jean-Paul Galmiche; Tamara Matysiak-B...
• Keywords: Fluorodeoxyglucose; Positron emission

Early detection is an essential prognostic factor in colorectal cancer (CRC) recurrence. Our aim was to evaluate diagnostic performances of (18)F-fluorodeoxyglucose-positron emission tomography ((18)F-FDG-PET)/computed (CT) as compared with CT the CRC recurrence.Data patients suspected recurrence and whom both FDG-PET/CT were performed analyzed. All detected lesions characterized according their number, size, localization. Positive histological or radiological follow-up considered 'gold standard'. Diagnostic calculated by lesion, globally respect site recurrence.One hundred seventy-six true-positive identified 71 patients. scan positive 58 (82%) 70 (98%) In per lesion analysis, global accuracy 88% (sensitivity = 95%, specificity 54%), which higher than that (53%, sensitivity 55%, 43%), particularly case lymph nodes metastases (100 vs. 35%) locoregional 39%) (P<0.0001). modified clinical management 31 patients.FDG-PET/CT more sensitive for diagnosis can modify 40%