Diagnostic value of PET/CT is similar to that of conventional MRI and even better for detecting small peritoneal implants in patients with recurrent ovarian cancer

Ovarian Neoplasms Reproducibility of Results Middle Aged Magnetic Resonance Imaging Multimodal Imaging Sensitivity and Specificity 3. Good health 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Abdominal Neoplasms Positron-Emission Tomography Humans Female Neoplasm Recurrence, Local Radiopharmaceuticals Tomography, X-Ray Computed Aged Follow-Up Studies Pelvic Neoplasms
DOI: 10.1097/mnm.0b013e32834fc5bf Publication Date: 2012-02-22T10:55:30Z
ABSTRACT
The aim of this study was to evaluate the diagnostic value 2-(fluorine-18)-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT in comparison with MRI for detection recurrent ovarian cancer.Forty-seven patients suspected cancer recurrence after total ablative or cytoreductive surgery, as well neoadjuvant adjuvant chemotherapy, who had undergone (18)F-FDG imaging were recruited present study. All also underwent within a month same purpose. Recurrent abdomen and pelvis evaluated each 47 classified either distant metastasis local pelvic involving vaginal stump, peritoneal implants, supradiaphragmatic region, and/or abdominal lymph nodes. Special attention paid implants. These divided into five groups according size implants: less than 0.5 cm (group 1), 0.5-1 2), 1-2 3), 2-3 4), larger 3 5). findings compared abdominopelvic MR findings. Statistical analysis carried out using Wilcoxon signed rank test.Thirty-nine found have cancer. Both negative six patients. Overall sensitivity, specificity, positive predictive value, accuracy 97.5, 100, 87.5, 97.8%, respectively, whereas those 95, 85.7, 97.4, 75, 93.6%, respectively. For implants 2 3, values significantly better (P<0.05).The revealed that is similar conventional has greater small-to-medium-sized (<2 cm) MRI. This may affect surgical decision making.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (28)
CITATIONS (45)