Diagnostic value of PET/CT is similar to that of conventional MRI and even better for detecting small peritoneal implants in patients with recurrent ovarian cancer
Ovarian Neoplasms
Reproducibility of Results
Middle Aged
Magnetic Resonance Imaging
Multimodal Imaging
Sensitivity and Specificity
3. Good health
03 medical and health sciences
0302 clinical medicine
Fluorodeoxyglucose F18
Abdominal Neoplasms
Positron-Emission Tomography
Humans
Female
Neoplasm Recurrence, Local
Radiopharmaceuticals
Tomography, X-Ray Computed
Aged
Follow-Up Studies
Pelvic Neoplasms
DOI:
10.1097/mnm.0b013e32834fc5bf
Publication Date:
2012-02-22T10:55:30Z
AUTHORS (11)
ABSTRACT
The aim of this study was to evaluate the diagnostic value 2-(fluorine-18)-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT in comparison with MRI for detection recurrent ovarian cancer.Forty-seven patients suspected cancer recurrence after total ablative or cytoreductive surgery, as well neoadjuvant adjuvant chemotherapy, who had undergone (18)F-FDG imaging were recruited present study. All also underwent within a month same purpose. Recurrent abdomen and pelvis evaluated each 47 classified either distant metastasis local pelvic involving vaginal stump, peritoneal implants, supradiaphragmatic region, and/or abdominal lymph nodes. Special attention paid implants. These divided into five groups according size implants: less than 0.5 cm (group 1), 0.5-1 2), 1-2 3), 2-3 4), larger 3 5). findings compared abdominopelvic MR findings. Statistical analysis carried out using Wilcoxon signed rank test.Thirty-nine found have cancer. Both negative six patients. Overall sensitivity, specificity, positive predictive value, accuracy 97.5, 100, 87.5, 97.8%, respectively, whereas those 95, 85.7, 97.4, 75, 93.6%, respectively. For implants 2 3, values significantly better (P<0.05).The revealed that is similar conventional has greater small-to-medium-sized (<2 cm) MRI. This may affect surgical decision making.
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