Diagnostic value of PET/CT is similar to that of conventional MRI and even better for detecting small peritoneal implants in patients with recurrent ovarian cancer

• DOI: 10.1097/mnm.0b013e32834fc5bf
• Publication Date: 2012-02-22T10:55:30Z
• Authors: Yasemin Sanli; Cuneyt Turkmen; Baris Bakir; Cem İyibozkurt; Sevda Ozel; Duygu Has; Ebru Yilmaz; Samet Topuz; Ekrem Yavuz; Seher Nilgun Unal; Ayse Mudun
• Keywords: Ovarian Neoplasms; Reproducibility of Results; Middle Aged; Magnetic Resonance Imaging; Multimodal Imaging; Sensitivity and Specificity; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Fluorodeoxyglucose F18; Abdominal Neoplasms; Positron-Emission Tomography; Humans; Female; Neoplasm Recurrence, Local; Radiopharmaceuticals; Tomography, X-Ray Computed; Aged; Follow-Up Studies; Pelvic Neoplasms

The aim of this study was to evaluate the diagnostic value 2-(fluorine-18)-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET/CT in comparison with MRI for detection recurrent ovarian cancer.Forty-seven patients suspected cancer recurrence after total ablative or cytoreductive surgery, as well neoadjuvant adjuvant chemotherapy, who had undergone (18)F-FDG imaging were recruited present study. All also underwent within a month same purpose. Recurrent abdomen and pelvis evaluated each 47 classified either distant metastasis local pelvic involving vaginal stump, peritoneal implants, supradiaphragmatic region, and/or abdominal lymph nodes. Special attention paid implants. These divided into five groups according size implants: less than 0.5 cm (group 1), 0.5-1 2), 1-2 3), 2-3 4), larger 3 5). findings compared abdominopelvic MR findings. Statistical analysis carried out using Wilcoxon signed rank test.Thirty-nine found have cancer. Both negative six patients. Overall sensitivity, specificity, positive predictive value, accuracy 97.5, 100, 87.5, 97.8%, respectively, whereas those 95, 85.7, 97.4, 75, 93.6%, respectively. For implants 2 3, values significantly better (P<0.05).The revealed that is similar conventional has greater small-to-medium-sized (<2 cm) MRI. This may affect surgical decision making.