Cow's Milk Allergy, Asthma, and Pediatric IBD
Male
0301 basic medicine
0303 health sciences
Adolescent
Infant
Inflammatory Bowel Diseases
Asthma
3. Good health
03 medical and health sciences
Crohn Disease
Risk Factors
Case-Control Studies
Child, Preschool
Odds Ratio
Humans
Colitis, Ulcerative
Female
Registries
Milk Hypersensitivity
Child
Finland
DOI:
10.1097/mpg.0b013e318285e9d8
Publication Date:
2013-01-12T10:46:16Z
AUTHORS (3)
ABSTRACT
ABSTRACTWe identified a total of 595 Finnish children born in 1994–2008 and diagnosed as having inflammatory bowel disease (IBD) by October 2010 from the National Reimbursement Register (based on certificates including the diagnostic criteria) to determine whether the presence of cow's milk allergy (CMA) or asthma is associated with the risk of contracting IBD (altogether 2380 matched controls). A diagnosis of CMA in infancy was associated with Crohn disease (odds ratio [OR] 1.92, confidence interval [CI] 1.09–3.36, P < 0.05) and ulcerative colitis (OR 1.71, CI 1.04–2.83, P < 0.05), but childhood asthma only with Crohn disease (OR 2.33, CI 1.41–3.86, P = 0.001). Thus, CMA in infants is a risk factor for contracting pediatric IBD and accordingly, asthma for Crohn disease.
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