Hematologic Manifestations of Brucellosis in Children: 5 Years Experience of an Anatolian Center

• DOI: 10.1097/mph.0b013e3181ced382
• Publication Date: 2010-02-27T06:03:30Z
• Authors: Elvan Caglar Citak; Funda Erkasar Citak; Bilge Tanyeri; Dilek Arman
• Keywords: Thrombocytopenic purpura

Brucellosis continues to be an important cause of fever in underdeveloped countries and the rural areas developed world. It is a multisystemic disease, associated with wide variety symptoms. A symptoms, including hematologic abnormalities, such as anemia, thrombocytopenia, pancytopenia, dissemine intravascular coagulation, leucopenia could seen. The aim study review findings brucellosis childhood.In this short study, records 146 children were evaluated for manifestation retrospectively. Among them, 9 patients had pancytopenia 5 brucella-induced immune thrombocytopenia identified 5-year period between June 2004 July 2009.Eight Brucella melitensis isolated from blood cultures and/or bone marrow cultures, all agglutination titers at least 1:320. All positive Brucella. Except 1 patient these regressed completely their peripheral counts returned normal after treatment infection. One was not responding brucella underwent allogeneic hematopoietic stem cell transplantation. thrombocytic purpura symptomatic severe they placed on intravenous gamma globulin 2 days. Between day 3 platelet increased patients.Brucellosis should considered possible diagnosis among thrombocytopenic endemic regions.