Kasabach-Merritt Phenomenon

• DOI: 10.1097/mph.0b013e318281558e
• Publication Date: 2013-02-06T15:16:45Z
• Authors: Naoko Yasui; Katsuyoshi Koh; Motohiro Kato; Myoung-ja Park; Daisuke Tomizawa; Koichi Oshima; Naoki Uchisaka; Yoshihiro Gocho; Ayumu Arakawa; Masafumi Seki; Eiji Oguma; Hiroshi Kishimoto; Shoji Watanabe; Akira Kikuchi; Ryoji Hanada
• Keywords: Phenomenon; Kasabach–Merritt syndrome

Kasabach-Merritt phenomenon (KMP) is a rare condition and optimal treatments have not yet been established, especially for cases that are unresponsive to first-line therapy. We retrospectively reviewed 11 KMP treated over the past 13 years in our institute.With exception of 1 case, steroids were administered as Eight required second-line or third-line The effective salvage therapies include interferon (n=1), radiotherapy chemotherapy (n=5). One case continues depend upon chemotherapy. Three refractory therapy dependent year age, whereas 8 effectively by 6 months age.Chemotherapy seems be most steroid-resistant cases.