Multicenter cohort study of in-hospital pediatric cardiac arrest*

• DOI: 10.1097/pcc.0b013e3181a7045c
• Publication Date: 2009-09-08T07:21:10Z
• Authors: Kathleen L. Meert; Amy Donaldson; Vinay Nadkarni; Kelly S. Tieves; Charles L. Schleien; Richard J. Brilli; Robert S. B. Clark; Donald H. Shaffner; Fiona Levy; Kimberly Statler; Heidi J. Dalton; Elise W. van der ...; Richard Hackbarth; Robert Pretzlaff; Lynn Hernan; J Michael Dean; Frank W. Moler
• Keywords: Male; Chi-Square Distribution; Adolescent; Infant, Newborn; Infant; Cardiopulmonary Resuscitation; United States; Heart Arrest; 3. Good health; Survival Rate; Logistic Models; Risk Factors; Child, Preschool; Humans; Female; Hospital Mortality; Child; Retrospective Studies

Objectives: 1) To describe clinical characteristics, hospital courses, and outcomes of a cohort children cared for within the Pediatric Emergency Care Applied Research Network who experienced in-hospital cardiac arrest with sustained return circulation between July 1, 2003 December 31, 2004, 2) to identify factors associated mortality in this population. These data are required prepare randomized trial therapeutic hypothermia on neurobehavioral after arrest. Design: Retrospective study. Setting: Fifteen children's hospitals Network. Patients: Patients 1 day 18 years age had cardiopulmonary resuscitation received chest compressions >1 min, >20 mins. Interventions: None. Measurements Main Results: A total 353 patients met entry criteria; 172 (48.7%) survived discharge. Among survivors, 132 (76.7%) good neurologic outcome documented by Cerebral Performance Category scores. After adjustment age, gender, first rhythm, variables available before during that were independently increased included pre-existing hematologic, oncologic, or immunologic disorders, genetic metabolic presence an endotracheal tube arrest, use sodium bicarbonate Variables decreased postoperative resuscitation. Extending time frame include before, during, 12 hours following calcium higher minimum blood pH pupillary responsiveness. Conclusions: Many among circulation. Such must be considered when designing pediatric patients.