National Expansion of Antiretroviral Treatment in Thailand, 2000-2007: Program Scale-Up and Patient Outcomes

• DOI: 10.1097/qai.0b013e3181967602
• Publication Date: 2009-05-21T12:43:18Z
• Authors: Sanchai Chasombat; Michelle S McConnell; Umaporn Siangphoe; Porntip Yuktanont; Thidaporn Jirawat...; Kimberley Fox; Sombat Thanpraser...; Philip A Mock; Peeramon Ningsanond; Cheewanan Lertpir...; Somchai Pinyoporn...
• Keywords: Antiretroviral treatment

Thailand began a national antiretroviral (ARV) treatment program in 2000, and all government some private university hospitals now provide to eligible HIV-infected patients. We describe scale-up patient outcomes from 2000 2007.Data 839 76 provinces of were included this analysis. Outcomes assessed for patients initiating ARV January December 2005. Follow-up data through March 2007 included; lost follow-up was defined as >3 months late visit. A Cox proportional hazard model used assess risk factors death; the Kaplan-Meier method estimate survival probabilities.Outcome are reported 58,008 Among these, 52.2% male; at initiation, median age 34 years, CD4 count 41 cells per cubic millimeter, 50.5% had AIDS. The initial regimen nevirapine 2 nonnucleoside reverse transcriptase inhibitors 92.4% patients; time 1.6 years (interquartile range = 0.8-2.4 years). Lost occurred 8.8% Overall 1-year 0.89 (95% confidence interval 0.88 0.89). Death significantly associated with male sex, >40 baseline <100 symptomatic HIV or AIDS, receipt services district community hospital, initiation before 2005.National programs can be scaled up rapidly good outcomes. Treatment among comparable those smaller cohorts other countries, rates have improved since 2004.