Effect of Clinical History in Focal Liver Lesion Detection and Classification on 4-Detector Row Computed Tomography and Gadoxetic Acid Enhanced MR Imaging in Oncologic Patients

• DOI: 10.1097/rct.0b013e3181a63e1e
• Publication Date: 2009-11-19T17:38:24Z
• Authors: Antonella Filippone; Roberta Cianci; Roberto Iezzi; Margherita Legnini; Maria Luigia Storto
• Keywords: Gadoxetic acid

To determine the influence of clinical data on reader diagnostic accuracy in focal liver lesion (FLL) detection and classification.Eighty-seven oncologic patients with FLLs underwent contrast-enhanced multidetector-row computed tomography (MDCT) gadoxetic acid-enhanced magnetic resonance imaging (MRI). Two independent readers reviewed images for FLL classification as benign or malignant without knowledge after provision information. The sensitivity, specificity, accuracy, Az values were calculated using intraoperative ultrasound pathologic findings standard reference.The awareness significantly improved (p = 0.02 both readers) 0.03 1 p 0.04 2) MDCT lesions a diameter cm less. When considering MRI, produced an improvement readers, although differences not significant.For classification, decrease 0.07 0.06 because associated increase false-positive findings. detecting classifying patients, does change performance when whereas, MDCT, it improves rate but produces diagnosis malignancy.