Factors Associated With Disability in Patients With Rheumatoid Arthritis

• DOI: 10.1097/rhu.0b013e3181e92d25
• Publication Date: 2010-06-23T07:31:14Z
• Authors: Emilce E. Schneeb...; Gustavo Citera; José A. Maldonado...; Mariana Salcedo; Flavia Chiardola; Marcos G. Rosemffet; María F. Marengo; Silvia Papasidero; Rafael Chaparro d...; Oscar L. Rillo; Verónica Bellomio; Eleonora Lucero; Alberto Spindler; Alberto Berman; Damian Duartes Noe; Juan C. Barreira; María A. Lázaro; Sergio O. Paira
• Keywords: Interquartile range

Analyze disability determinants in a cohort of Argentine patients with rheumatoid arthritis (RA).Consecutive RA, according to ACR'87 criteria, were recruited from 6 rheumatology centers. Demographic and socioeconomic data, family history, comorbid diseases, extra-articular manifestations information about received treatments provided. Disease activity was assessed using Activity Score 28 (DAS 28) the Health Assessment Questionnaire (HAQ)-A used for functional capacity. Hand feet radiographs Sharp-van der Heijde score.A total 640 RA included, which 85.2% females. Mean age 53 years (interquartile range [IQR], 44-62) mean disease duration 8 (IQR, 4-14). DAS 2.72 1.7-3.7) HAQ-A 0.62 0.13-1.25). Multiple linear regression showed that main variables associated 28, radiologic damage age. Main predictors multiple logistic severe HAQ (>2) as dependent variable (OR, 2; P < 0.0001); 1; = 0.008); structural 0.001).In this population, highest impact on physical function. Radiologic affected progressed.