Predictive Factors for Lymph Node Metastasis in Early Gastric Cancer With Submucosal Invasion

• DOI: 10.1097/sla.0b013e31811f3fb7
• Publication Date: 2009-03-03T23:41:05Z
• Authors: Ji Yeong An; Yong Hae Baik; Min Gew Choi; Jae Hyung Noh; Tae Sung Sohn; Sung Kim
• Keywords: Lymphovascular invasion; Perineural invasion

In Brief Objective: An accurate assessment of a potential lymph node metastasis is an important issue for the appropriate treatment early gastric cancer. Minimizing amount invasive procedures used in cancer critical improving patient's quality life. Therefore, this study analyzed predictive risk factors with submucosal invasion. Methods: The data from 1043 patients surgically treated invasion between 2002 and 2005 were reviewed retrospectively. divided into 3 layers according to their depth: SM1, SM2, SM3. clinicopathological variables predicting evaluated. Results: A was observed 19.4% patients. tumor size, histologic type, Lauren classification, depth, perineural showed positive correlation rate N category by univariate analysis. Multivariate analyses revealed size (≥2 cm) lymphatic involvement be significantly independently related metastasis. presence strongest factor metastasis, being 43.8% cases which had been revealed. No 12 no involvement, SM1 invasion, <1 cm. Conclusions: Lymphatic are independent Minimal treatment, such as endoscopic mucosal resection, may possible highly selective cancers study,