Hepatic Metastases From Neuroendocrine Tumors With a “Thin Slice” Pathological Examination

• DOI: 10.1097/sla.0b013e3181bdf8cf
• Publication Date: 2010-01-21T07:06:05Z
• Authors: Dominique Elias; Jérémie H. Lefevre; Pierre Duvillard; Diane Goéré; Clarisse Dromain; Frédéric Dumont; Eric Baudin
• Keywords: Palpation

To prospectively compare the results of pathologic examination including thin 3- to 4-mm thick serial slices surgical specimen in a well-defined anatomic part liver with those 4 different imaging techniques. BACKGROUNDS SUMMARY DATA: Liver metastases (LM) neuroendocrine origin are frequent and accuracy pretherapeutic detecting small-sized LM is questioned, but no study has compared techniques used image large specimens meticulous examination.Eleven patients metastatic endocrine tumor were selected before undergoing right hepatectomy or left passing along median hepatic vein. Before hepatectomy, underwent somatostatin receptor scintigraphy, computed tomography, magnetic resonance imaging, ultrasonography (US). An intraoperative assessment (palpation US) was also performed. systematically cut into slices, thick. A final histologic count total number obtained findings from each technique.Compared LM, fewer than 50% detected preoperatively. The 24% for 38% tomography US, 49% (the only technique that half LM). size smallest not greater 2 mm 54% patients.Half tumors undetectable on preoperative imaging.