Achieving Donor Management Goals Before Deceased Donor Procurement Is Associated With More Organs Transplanted Per Donor

• DOI: 10.1097/ta.0b013e31822779e5
• Publication Date: 2011-07-30T17:12:17Z
• Authors: Darren J. Malinoski; Michael C. Daly; Madhukar S. Patel; Chrystal Oley-Gra...; Clarence E. Foster; Ali Salim
• Keywords: Organ procurement

There is a national shortage of organs available for transplantation. Implementation preset donor management goals (DMGs) to improve outcomes recommended, but uniform practices and data are lacking. We hypothesized that meeting DMGs before organ procurement would result in more transplanted per (OTPD).The eight organization United Network Organ Sharing Region 5 selected 10 critical care end points as DMGs. Each submitted retrospective from 40 standard criteria donors. "DMGs met" was defined achieving any procurement. The primary outcome ≥4 OTPD. Binary logistic regression used determine independent predictors OTPD with p<0.05.Three hundred twenty donors had 3.6±1.6 Donors met (4.4 vs. 3.3, p<0.001) were likely have (70% 39%, p<0.001). Independent age (odds ratio [OR]=0.94), serum creatinine (OR=0.65), thyroid hormone use (OR=2.0), (OR=4.4), the following individual DMGs: central venous pressure 4 mm Hg (OR=1.9), ejection fraction>50% (OR=4.0), Pao2:FIO2>300 (OR=4.6), sodium 135 160 mEq/L (OR=3.4).Meeting resulted Donor factors yield. Prospective studies needed true impact each DMG on number function organs.