Rapidly Progressive Dementia

• DOI: 10.1097/wad.0b013e31819e099b
• Publication Date: 2010-01-27T05:54:31Z
• Authors: Sokratis G. Papag...; Theodoros Kontaxis; Anastasios Bonakis; Georgios Karahalios; Nikolaos Kalfakis; Demetrios Vassilo...
• Keywords: Vascular dementia

Dementia is generally considered as rapidly progressive [rapidly dementia (RPD)], in cases with overt cognitive impairment, established within months. Data about the relative frequency of underlying diseases RPD are few and extremely variable, depending on clinical setting. We examined causes RPD, a university tertiary referral center, Athens. A series consecutive patients presenting 3-year period was included. All received comprehensive clinical, imaging, laboratory evaluation. Of total 279 hospitalized for diagnosis, 68 had (37 males 31 females). Mean age at onset ±SD 65.5±10.0. The most common cause secondary dementias, accounting 18 (26.5%). Alzheimer disease frontotemporal were almost equally represented, 12 (17.6%) 11 (16.2%) cases, respectively. Vascular dementia, Creutzfeldt-Jakob disease, various neurodegenerative accounted 9 each (13.2%). In dementias represented frequent RPD. As substantial number these potentially treatable, our finding reconfirms underscores importance an exhaustive evaluation any case