Detection of enterovirus 68 as one of the commonest types of enterovirus found in patients with acute respiratory tract infection in China

• DOI: 10.1099/jmm.0.068247-0
• Publication Date: 2013-12-10T03:58:49Z
• Authors: Qing-Bin Lu; Ying Wo; Hong-Yu Wang; Mao-Ti Wei; Lei Zhang; Hong Yang; En-Mei Liu; Ting-Yu Li; Zhong-Tang Zhao; Wei Liu; Wu-Chun Cao
• Keywords: Rhinovirus; Echovirus; Respiratory tract; Coxsackievirus; Enterovirus 71; Hepatitis E Virus

Human enterovirus 68 (HEV-68) is an associated with respiratory illness. In China, no information about HEV-68 available for children yet. This study aimed to investigate the presence of in mainland China between 2009 and 2012 explore migration events across world. Among 1565 samples tested from children, 41 (2.6%) were positive HEV 223 (14.3%) human rhinovirus (HRV). Seven (17.1%) HEVs HEV-68. Two HEV-68- five HRV-positive detected 585 adult samples. predominant type acute tract infection (ARTI), followed by HEV-71 coxsackievirus A6. Three HEV-68-infected presented severe pneumonia one a asthma attack. The viruses attributed two novel distinct sublineages based on phylogenetic analysis partial VP1 gene sequences. Migration showed that USA Netherlands possible geographical sources HEV-68, where three strains migrated China. conclusion, may play role among enteroviruses ARTI children. Additional surveillance needed clarify reason why causes such wide spectrum disease, asymptomatic disease even death.