Aetiology, epidemiology and clinical characteristics of acute moderate-to-severe diarrhoea in children under 5 years of age hospitalized in a referral paediatric hospital in Rabat, Morocco
Diarrhea
Male
0301 basic medicine
Infants malalts
Infant
Sick children
Bacterial Infections
Hospitals, Pediatric
3. Good health
Hospitalization
Tertiary Care Centers
Morocco
03 medical and health sciences
0302 clinical medicine
Virus Diseases
Child, Preschool
Parasitic Diseases
Prevalence
Humans
Marroc
Female
Prospective Studies
Diarrea
DOI:
10.1099/jmm.0.079830-0
Publication Date:
2014-11-29T03:19:05Z
AUTHORS (14)
ABSTRACT
The objective of the study was to describe the aetiology, epidemiology and clinical characteristics of the principal causes of acute infectious diarrhoea requiring hospitalization among children under 5 years of age in Rabat, Morocco. A prospective study was conducted from March 2011 to March 2012, designed to describe the main pathogens causing diarrhoea in hospitalized children >2 months and less than 5 years of age. Among the 122 children included in the study, enteroaggregative Escherichia coli (EAEC) and rotavirus were the main aetiological causes of diarrhoea detected. Twelve (9.8 %) children were referred to an intensive care unit, while two, presenting infection by EAEC, and EAEC plus Shigella sonnei, developed a haemolytic uraemic syndrome. Additionally, six (4.9 %) deaths occurred, with EAEC being isolated in four of these cases. Diarrhoeagenic E. coli and rotavirus play a significant role as the two main causes of severe diarrhoea, while other pathogens, such as norovirus and parasites, seem to have a minimal contribution. Surveillance and prevention programmes to facilitate early recognition and improved management of potentially life-threatening diarrhoea episodes are needed.
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