The first case report of septic abortion resulting from β-lactamase-negative ampicillin-resistant non-typeable Haemophilus influenzae infection

• DOI: 10.1099/jmmcr.0.005123
• Publication Date: 2017-10-12T11:15:15Z
• Authors: Hiroaki Baba; Risako Kakuta; Hasumi Tomita; Minako Miyazoe; Masatoshi Saito; Chihiro Oe; Noriomi Ishibashi; Misa Sogi; Kengo Oshima; Tetsuji Aoyagi; Yoshiaki Gu; Makiko Yoshida; Koichi Tokuda; Shiro Endo; Hisakazu Yano; Mitsuo Kaku
• Keywords: Septic abortion

Introduction. This is the first case report of septic abortion due to β-lactamase-negative ampicillin-resistant (BLNAR) non-typeable Haemophilus influenzae infection. In Japan, BLNAR H. widespread and has become a clinical concern, especially in paediatrics otolaryngology, but not been previously recognized as causative agent obstetric or gynaecological Case presentation. A 31-year-old pregnant woman presented at 17 weeks 6 days gestation with high fever; she was admitted diagnosis threatened premature delivery. Despite tocolytic treatment, aborted spontaneously 2 h after admission then entered shock. detected both blood vaginal cultures. Her condition gradually improved several treatment cefotaxime, ultimately discharged without sequelae complaints. Conclusion. Although penicillin β-lactamase inhibitor currently recommended for abortion, this combination will probably lead failure As study reveals, can cause abortion; hence, future efforts should be undertaken detect therapeutically target pathogen during pregnancy.