ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria

• DOI: 10.1099/mgen.0.000824
• Publication Date: 2022-07-01T14:16:17Z
• Authors: Morgan Anne Feeney; Jake Terry Newitt; Emily Addington; Lis Algora-Gallardo; Craig Allan; Lucas Balis; Anna S. Birke; Laia Castaño-Espriu; Louise K. Charkou...; Rebecca Devine; Damien Gayrard; Jacob Hamilton; Oliver Hennrich; Paul A. Hoskisson; Molly Keith-Baker; Joshua G. Klein; Worarat Kruasuwan; David R. Mark; Yvonne Mast; Rebecca E. McHugh; Thomas C. McLean; Elmira Mohit; John T. Munnoch; Jordan Murray; Katie Noble; Hiroshi Otani; Jonathan Parra; Camila F. Pereira; Louisa Perry; Linamaria Pintor-...; Leighton Pritchard; Samuel M. M. Prud...; Alicia H. Russell; Jana K. Schniete; Ryan F. Seipke; Nelly Sélem-Mojica; Agustina Undabarrena; Kristiina Vind; Gilles P. van Wezel; Barrie Wilkinson; Sarah F. Worsley; Katherine R. Duncan; Lorena T. Fernánd...; Matthew I. Hutchings
• Keywords: 0301 basic medicine; 570; RM; Phylum; Resource (disambiguation); Microbiology; antibiotics; 03 medical and health sciences; Biochemistry, Genetics and Molecular Biology; Health Sciences; Bioresources; Genetics; RNA Sequencing Data Analysis; Molecular Biology; Biology; Pharmacology; Computer network; 0303 health sciences; Ecology; Bacteria; Marine Microbial Diversity and Biogeography; 500; Life Sciences; actinobacteria; Natural Products as Sources of New Drugs; Biological Sciences; Computer science; Streptomyces; BGCs; QR; Anti-Bacterial Agents; Functional Genomics; Process (computing); Actinobacteria; Operating system; Infectious Diseases; CRISPR; FOS: Biological sciences; Environmental Science; Physical Sciences; Medicine; Therapeutics. Pharmacology; Generic health relevance; specialised metabolites; Biotechnology; 16S ribosomal RNA

Actinobacteria is an ancient phylum of Gram-positive bacteria with a characteristic high GC content to their DNA. The ActinoBase Wiki focused on the filamentous actinobacteria, such as Streptomyces species, and techniques growth conditions used study them. These organisms are studied because complex developmental life cycles diverse specialised metabolism which produces many antibiotics currently in clinic. community effort that provides valuable freely accessible resources, including protocols practical information about actinobacteria. It aimed at enabling knowledge exchange between members international research working these fascinating bacteria. anchor platform underpins worldwide efforts understand ecology, biology metabolic potential organisms. There two key differences set apart from other Wiki-based platforms: [1] specifically researchers actinobacteria tailored help users overcome challenges [2] it resource global networking opportunities for broad range experience this field.