Analysis of cassava brown streak viruses reveals the presence of distinct virus species causing cassava brown streak disease in East Africa
0301 basic medicine
Manihot
Genotype
Sequence Homology, Amino Acid
Molecular Sequence Data
Potyvirus
Genome, Viral
Sequence Analysis, DNA
Africa, Eastern
Cross Reactions
Antibodies, Viral
3. Good health
03 medical and health sciences
Sequence Homology, Nucleic Acid
Cluster Analysis
RNA, Viral
Capsid Proteins
Phylogeny
Plant Diseases
DOI:
10.1099/vir.0.014688-0
Publication Date:
2010-01-14T02:45:28Z
AUTHORS (6)
ABSTRACT
Cassava brown streak virus (CBSV) isolates were analysed from symptomatic cassava collected between 1997 and 2008 in the major cultivation regions of East Africa. An analysis complete RNA genomes seven Kenya, Tanzania, Mozambique, Uganda Malawi revealed a common genome structure, but clearly clustered two distinct clades. The first comprised Uganda, Malawi, north-western Tanzania CBSV described previously, shared 87 95% nucleotide sequence identity, whilst second included coastal Mozambique which only 70% identities with clade. When amino acid sequences viral proteins compared, as low 47% (Ham1) 59% (P1) clades found. antiserum obtained against capsid protein clade 1 isolate identified 43 kDa 45 2 isolates. Several cultivars susceptible to resistant those 1. differences observed both biological behaviour genomic indicate that disease Africa is caused by at least species. It suggested retain species name virus, be classified virus.
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CITATIONS (169)
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