Molecular characterization of Porcine circovirus type 2 isolates from post-weaning multisystemic wasting syndrome-affected and non-affected pigs

• DOI: 10.1099/vir.0.19536-0
• Publication Date: 2004-02-09T22:07:58Z
• Authors: Claire de Boisséson; Véronique Béven; Laurent Bigarré; Richard Thiéry; Nicolas Rose; Eric Eveno; François Madec; André Jestin
• Keywords: Circovirus; Wasting Syndrome

Porcine circovirus type 2 (PCV2) is recognized as a primary cause in post-weaning multisystemic wasting syndrome (PMWS). In this study, both PCV1 and PCV2 types were studied pigs originating from PMWS-affected (+) non-affected (−) herds Brittany. was identified by PCR 100 % of animals PMWS(+) 76 PMWS(−) herds, while not detected. The complete sequences 38 isolates determined 23 new variants identified, displaying between 94·6 99·9 nucleotide identity with one another. Although highly related to all the available databases, France gathered distinct subcluster. Compared 13 farms, 10 exhibited slightly higher variability. No viral molecular marker specific pathogenic state could be even including other isolated PMWS-suffering countries. We concluded that PMWS outbreaks Brittany are most likely due emergence genotype circovirus.