Effects of Prenatal Stress on Structural Brain Development and Aging in Humans

• DOI: 10.1101/148916
• Publication Date: 2017-06-13T05:10:12Z
• Authors: Katja Franke; Bea van den Bergh; Susanne R. de Rooij; Tessa J. Roseboom; Peter W. Nathanielsz; Otto W. Witte; Matthias Schwab
• Keywords: Prenatal Stress; Brain Aging; Genetic predisposition; Brain Development

Abstract Healthy brain aging is a major determinant of quality life, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to lifestyle genetic factors, environmental influences prenatal life have impact on age-associated disorders. The aim this review summarize the existing literature consequences maternal anxiety, stress, malnutrition for structural predisposition diseases, focusing with human samples. In conclusion, results underscore importance healthy mother-child relationship, starting pregnancy, need early interventions if relationship compromised.