3Dmapper: A Command Line Tool For BioBank-scale Mapping Of Variants To Protein Structures

Python
DOI: 10.1101/2023.09.01.555502 Publication Date: 2023-09-05T08:20:10Z
ABSTRACT
ABSTRACT The interpretation of genomic data is crucial to understand the molecular mechanisms biological processes. Protein structures play a vital role in facilitating this by providing functional context genetic coding variants. However, mapping genes proteins tedious and error-prone task due inconsistencies formats. Over past two decades, numerous tools databases have been developed automatically map annotated positions variants protein structures. most these are web-based not well-suited for large-scale analysis. To address issue, we introduce 3Dmapper, standalone command-line tool Python R. It systematically maps structures, solution that both efficient reliable. 3Dmapper freely available on GitHub at https://github.com/vicruiser/3Dmapper .
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