North-south pathways, emerging variants, and high climate suitability characterize the recent spread of dengue virus serotypes 2 and 3 in the Dominican Republic

Preparedness
DOI: 10.1101/2024.02.14.24302795 Publication Date: 2024-02-15T22:10:27Z
ABSTRACT
We employ a multidisciplinary approach, integrating genomics and epidemiology, to uncover recent dengue virus transmission dynamics in the Dominican Republic. Our results highlight previously unknown north-south pathway within country, with co-circulation of multiple lineages. Additionally, we examine historical climate data, revealing long-term trends towards higher theoretical potential for due rising temperatures. These findings provide information targeted interventions resource allocation, informing as well preparedness strategies public health agencies mitigating geo-related risks.
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