Physics of adherent cells

• DOI: 10.1103/revmodphys.85.1327
• Publication Date: 2013-08-27T21:44:06Z
• Authors: Ulrich S. Schwarz; Samuel A. Safran
• Keywords: Soft materials; Active matter; Soft matter

One of the most unique physical features cell adhesion to external surfaces is active generation mechanical force at cell-material interface. This includes pulling forces generated by contractile polymer bundles and networks, pushing polymerization networks. These are transmitted substrate mainly focal adhesions, which large, yet highly dynamic clusters. Tissue cells use these sense properties their environment communicate with each other. The effect intricately linked material environment. Here a review given recent progress in our understanding role from viewpoint theoretical soft matter physics close relation relevant experiments.