Comorbid burden at ICU admission in COVID‐19 compared to sepsis and acute respiratory distress syndrome

• DOI: 10.1111/aas.14514
• Publication Date: 2024-08-26T07:25:06Z
• Authors: Björn Ahlström; Robert Frithiof; Ing‐Marie Larsson; Gunnar Strandberg; Miklos Lipcsey; Michael Hultström
• Keywords: Male; Adult; hypertension; Anestesi och intensivvård; heart disease; Comorbidity; chronic obstructive pulmonary disease; sepsis; Cohort Studies; 03 medical and health sciences; 0302 clinical medicine; COVID‐19; Risk Factors; Sepsis; Humans; Registries; Aged; Sweden; Aged, 80 and over; Respiratory Distress Syndrome; diabetes; Anesthesiology and Intensive Care; COVID-19; acute respiratory distress syndrome; asthma; Middle Aged; critical care; comorbidity; Intensive Care Units; Female

Abstract Background Comorbidities are similarly associated with short‐term mortality for COVID‐19, acute respiratory distress syndrome (ARDS) and sepsis in intensive care unit (ICU) patients, but their adjusted frequencies at admission unknown. Thus, we aimed to evaluate the distribution, reported as odds ratios, of known risk factors (i.e., age, sex comorbidities) ICU between ARDS patients this nationwide registry‐based study. Methods In cohort study, included adult admitted Swedish ICUs COVID‐19 ( n = 7382) during pandemic compared them 22,354) or 2776) a pre‐COVID‐19 period. The main outcomes were comorbidities, sex, age multivariable logistic regression on diagnostic categories ICU, ARDS. Results We found that most well had stronger association than exception male type 2 diabetes mellitus, asthma more strongly admission, while no difference was seen chronic renal failure obesity. For except failure, obesity which whereas hypertension, obstructive pulmonary disease not different. Conclusions Patients carry heavier burden comorbidity high COVID‐19. This is likely caused by combination of: (1) being less dependent comorbidities other forms ARDS, cause critical illness infections causing (2) deferred situations where syndromes admitted.