Sensitivity, specificity, and tolerability of the BACTrack Skyn compared to other alcohol monitoring approaches among young adults in a field‐based setting

• DOI: 10.1111/acer.14804
• Publication Date: 2022-05-14T15:00:31Z
• Authors: Garrett I. Ash; Ralitza Gueorguieva; Nancy P. Barnett; Wuyi Wang; David S. Robledo; Kelly S. DeMartini; Brian Pittman; Nancy S. Redeker; Stephanie S. O’Ma...; Lisa M. Fucito
• Keywords: Tolerability; Scram

Abstract Background There is a need for novel alcohol biosensors that are accurate, able to detect concentration close in time consumption, and feasible acceptable many clinical research applications. We evaluated the field accuracy tolerability of (BACTrack Skyn ) established (Alcohol Monitoring Systems SCRAM CAM biosensors. Methods The sensor diary data were collected larger study biofeedback intervention compared observationally present sub‐study. Participants (high‐risk drinkers, 40% female; median age 21) wore both sensors 1–6 days instructed drink as usual. Data from first cohort participants ( N = 27; 101 person‐days) used find threshold values transdermal classified each day meeting or not defined levels drinking (heavy, above‐moderate, any). These develop scoring metrics subsequently tested using second 20; 57 person‐days). mobile self‐report evaluate sensitivity specificity relation priori standards literature. Results classification rules Cohort #1 within 3 months device shipment showed excellent heavy (94%) exceeded expectations above‐moderate any (78% 69%, respectively), while met (91%). However, worsened when devices ≥3 (area under curve receiver operator characteristic 0.87 vs. 0.79) derived applied #2 was inadequately specific (70%). p ≤ 0.001). Conclusions favorable internally derivable but did yield useful going forward across lots usage.