Arrhythmia associated with buprenorphine and methadone reported to the food and drug administration

• DOI: 10.1111/add.13013
• Publication Date: 2015-06-15T10:44:55Z
• Authors: David P. Kao; Mark C. P. Haigney; Philip S. Mehler; Mori J. Krantz
• Keywords: Adult; Male; United States Food and Drug Administration; Narcotic Antagonists; Arrhythmias, Cardiac; United States; Buprenorphine; Heart Arrest; 3. Good health; Long QT Syndrome; Torsades de Pointes; Humans; Female; Methadone; Retrospective Studies

To assess the relative frequency of reporting adverse events involving ventricular arrhythmia, cardiac arrest, corrected QT interval (QTc) prolongation or torsade de pointes to US Food and Drug Administration (FDA) between buprenorphine methadone.