Motivational interviewing and problem‐solving therapy intervention for patients on antiretroviral therapy for HIV in Tshwane, South Africa: A randomized controlled trial to assess the impact on alcohol consumption

• DOI: 10.1111/add.16278
• Publication Date: 2023-06-21T00:31:38Z
• Authors: Charles D. H. Parry; Bronwyn Myers; Mukhethwa Londani; Paul A. Shuper; Charl Janse van R...; Samuel O. M. Manda; Sebenzile Nkosi; Connie T. Kekwale...; Judith A. Hahn; Jürgen Rehm; Katherine Sorsdahl; Neo K. Morojele
• Keywords: Motivational Interviewing; Brief intervention; Intention-to-treat analysis

Abstract Background and Aims Reduction of alcohol consumption is important for people undergoing treatment HIV. We tested the efficacy a brief intervention reducing average volume consumed among patients on HIV antiretroviral therapy (ART). Design, Setting Participants This study used two‐arm multi‐centre randomized controlled trial with follow‐up to 6 months. Recruitment occurred between May 2016 October 2017 at six ART clinics public hospitals in Tshwane, South Africa. were living HIV, mean age 40.8 years [standard deviation (SD) = 9.07], 57.5% female, 6.9 (SD 3.62) ART. At baseline (BL), number drinks over past 30 days was 25.2 38.3). Of 756 eligible patients, 623 enrolled. Intervention randomly assigned motivational interviewing (MI)/problem‐solving (PST) arm (four modules MI PST delivered two sessions by interventionists) or as usual (TAU) comparison arm. People assessing outcomes masked group assignment. Measurements The primary outcome standard (15 ml pure alcohol) during assessed 6‐month (6MFU). Findings 305 participants MI/PST, 225 (74%) completed (all modules). 6MFU, retention 88% control 83% In support hypothesis, an intention‐to‐treat‐analysis 6MFU −0.410 (95% confidence interval −0.670 −0.149) units lower log scale than ( P 0.002), 34% relative reduction drinks. Sensitivity analyses undertaken who had use disorders identification test (AUDIT) scores ≥ 8 BL n 299). similar those whole sample. Conclusions Africa, interviewing/problem‐solving significantly reduced drinking levels HIV‐infected follow‐up.