Is COVID-19 infection more severe in kidney transplant recipients?
Univariate analysis
DOI:
10.1111/ajt.16424
Publication Date:
2020-12-01T23:44:38Z
AUTHORS (37)
ABSTRACT
There are no studies which have compared the risk of severe COVID-19 and related mortality between transplant recipients nontransplant patients. We enrolled two groups patients hospitalized for COVID-19, that is, kidney (KTR) from French Registry Solid Organ Transplant (n = 306) a single-center cohort 795). An analysis was performed among subgroups matched age factors or mortality. Severe defined as admission (or transfer) to an intensive care unit, need mechanical ventilation, death. were younger had more comorbidities They presented with higher creatinine levels developed episodes acute injury. After matching, 30-day cumulative incidence did not differ KTR patients; however, COVID-19-related significantly in (17.9% vs 11.4%, respectively, p .038). Age >60 years, cardiovascular disease, dyspnea, fever, lymphopenia, C-reactive protein (CRP) associated univariate analysis, whereas status serum not. hypertension, diabetes, CRP mg/L, (HR 1.55), level >115 µmol/L 2.32) analysis. In multivariable fever level>115 retained their independent associations
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