Characteristics of Specialist‐Diagnosed Asthma‐COPD Overlap in Severe Asthma: Observations from the Korean Severe Asthma Registry (KoSAR)

• DOI: 10.1111/all.14483
• Publication Date: 2020-07-06T15:31:10Z
• Authors: Hyun Lee; Sang‐Heon Kim; Byung‐Keun Kim; Youngsoo Lee; Hwa Young Lee; Ga‐Young Ban; Min‐Hye Kim; Joo‐Hee Kim; Jae‐Woo Kwon; So‐Young Park; Jae‐Woo Jung; So Young Park; Chan Sun Park; Chin Kook Rhee; Taehoon Lee; Jae‐Hyun Lee; So Ri Kim; Jong‐Sook Park; Heung‐Woo Park; Kwang Ha Yoo; Yeon‐Mok Oh; Young‐Il Koh; Byung‐Jae Lee; An‐Soo Jang; Sang‐Heon Cho; Hae‐Sim Park; Choon‐Sik Park; You Sook Cho; Ho Joo Yoon
• Keywords: asthma‐COPD overlap; severe asthma; Male; Asthma* / epidemiology; 610; Chronic Obstructive* / diagnosis; Chronic Obstructive* / epidemiology; registry; Asthma; 620; 3. Good health; Pulmonary Disease; Pulmonary Disease, Chronic Obstructive; 03 medical and health sciences; 0302 clinical medicine; Asthma* / diagnosis; Republic of Korea; Humans; Female; Registries; Republic of Korea / epidemiology; Specialization

Abstract Background While the clinical characteristics and outcomes of asthma‐chronic obstructive pulmonary disease (COPD) overlap (ACO) have been frequently compared with those COPD or asthma, prevalence features ACO in patients severe asthma are unclear. Objectives Evaluation using Korean registry. Methods At time registration, was determined by attending specialists. Patients were classified into non‐ACO groups, demographic these two groups compared. Results Of 482 23.7% had ACO. group more likely to be male ( P < .001), older ex‐ current smokers .001) group. lower mean forced expiratory volume 1 second blood eosinophil percentage = .006), but higher neutrophil .027) than The used inhaled long‐acting muscarinic antagonist methylxanthine sustained systemic corticosteroid .002). In addition, unscheduled emergency department visits due exacerbation frequent .006). Conclusion Among older, predominantly male, a smoking history only. exacerbations related