Association between ambient air pollution and development and persistence of atopic and non‐atopic eczema in a cohort of adults

• DOI: 10.1111/all.14783
• Publication Date: 2021-02-18T09:19:10Z
• Authors: Diego J. Lopez; Caroline J. Lodge; Dinh S. Bui; Nilakshi T. Waidy...; John C. Su; Jenny L. Perret; Luke D. Knibbs; Bircan Erbas; Paul S. Thomas; Garun S. Hamilton; Bruce R. Thompson; Michael J. Abramson; E. Haydn Walters; Shyamali C. Dharmage; Gayan Bowatte; Adrian J. Lowe
• Keywords: Persistence (discontinuity); Atopy

Abstract Background There is limited information on risk factors for eczema in adults. Recent evidence suggests that air pollution may be associated with increased incidence of We aimed to assess this possible association. Methods Ambient exposures (distance from a major road, nitrogen dioxide [NO 2 ], fine particulate matter an aerodynamic diameter ≤2.5 µm [PM 2.5 ]) were assessed the residential address Tasmanian Longitudinal Health Study participants at ages 43 and 53 years. Eczema (onset after age years), prevalence (at persistence surveys, while IgE sensitization was using skin prick tests. The presence or absence classified into four groups: no atopy eczema, alone, non‐atopic atopic eczema. Adjusted logistic multinomial regression models fitted estimate associations between ambient interaction by sex assessed. Results Of 3153 both follow‐ups, 2369 had valid For males, 2.3 ppb increase baselineNO odds prevalent (OR = 1.15 [95% CI 0.98–1.36]) 1.26 [1.00–1.59]). These not seen females ( p 0.08, <0.01). sexes, 1.6 µg/m 3 PM exposure follow‐up aeroallergen [1.03–1.30]). Conclusion Increased pollutants only genders.