Allergies and COVID‐19 vaccines: An ENDA/EAACI Position paper

• DOI: 10.1111/all.15241
• Publication Date: 2022-02-03T02:44:41Z
• Authors: Annick Barbaud; Lene Heise Garvey; Alessandra Arcolaci; Knut Brockow; Francesca Mori; Cristobalina Mayorga; Patrizia Bonadonna; Marina Atanaskovi...; Luis Moral; Giovanna Zanoni; Mauro Pagani; Angèle Soria; Maja Jošt; Jean‐Christoph Ca...; Abreu Carmo; Al‐Ahmad Mona; Alberto Alvarez‐P...; Sevim Bavbek; Biagioni Benedetta; M.Beatrice Bilo; Natalia Blanca‐López; Herrera Gádor Bogas; Alessandro Buonomo; Gianfranco Calogiuri; Giulia Carli; Josefina Cernadas; Gabriele Cortellini; Gülfem Celik; Semra Demir; Inmaculada Doña; Adile Berna Dursun; Bernadette Eberlein; Emilia Faria; Bryan Fernandes; Tomaz Garcez; Ignacio Garcia‐Nunez; Radoslaw Gawlik; Asli Gelincik; Eva Gomes; Jimmy H. C. Gooi; Martine Grosber; Theo Gülen; Florence Hacard; Cyrille Hoarau; Christer Janson; Sebastian L. John...; Lukas Joerg; Seçil Kepil Özdemir; Ludger Klimek; Mitja Košnik; Marek L. Kowalski; Semanur Kuyucu; Violeta Kvedariene; Jose Julio Laguna; Carla Lombardo; Susana Marinho; Hans Merk; Elisa Meucci; Martine Morisset; Rosa Munoz‐Cano; Francesco Murzilli; Alla Nakonechna; Florin‐Dan Popescu; Grzegorz Porebski; Anna Radice; Frederico S. Rega...; Heike Röckmann; Antonino Romano; Ravishankar Sargur; Joaquin Sastre; Kathrin Scherer H...; Lenka Sedláčková; Marta Sobotkova; Ingrid Terreehorst; Regina Treudler; Jolanta Walusiak‐...; Bettina Wedi; Stefan Wöhrl; Mihael Zidarn; Torsten Zuberbier; Ioana Agache; Maria J. Torres
• Keywords: Drug allergy

Anaphylaxis, which is rare, has been reported after COVID-19 vaccination, but its management not standardized.Members of the European Network for Drug Allergy and Academy Clinical Immunology interested in drug allergy participated an online questionnaire on pre-vaccination screening allergic reactions to vaccines, literature was analysed.No death due anaphylaxis vaccines confirmed scientific literature. Potential allergens, polyethylene glycol (PEG), polysorbate tromethamine are excipients. The authors propose evaluation persons with following histories: 1-anaphylaxis injectable or vaccine containing PEG derivatives; 2-anaphylaxis oral/topical products; 3-recurrent unknown cause; 4-suspected any mRNA vaccine; 5-confirmed derivatives. We recommend a prick-to-prick skin test left-over solution suspected vial avoid waste. Prick panel should include 4000 3500, 2000 80. value vitro arguable.These recommendations will lead better knowledge mechanisms involved enable more people history be vaccinated.