Seminal plasma miR‐210‐3p is a biomarker for screening dyszoospermia caused by varicocele

• DOI: 10.1111/and.13244
• Publication Date: 2019-02-04T02:30:15Z
• Authors: Yawei Xu; Yuanyuan Zhang; Yongjiao Yang; Xiaoqiang Liu; Yegang Chen
• Keywords: Semen Analysis; Univariate analysis

To evaluate the value of seminal plasma miR-210-3p as a novel and non-invasive biomarker for screening dyszoospermia caused by varicocele. Semen samples from patients with varicocele healthy males were collected semen analysis quantitative real-time polymerase chain reaction. Cox univariate multivariate receiver operating characteristic curve used to assess relationship between level impaired spermatogenic function. Our results showed that in was 2.18 times control group (p < 0.001), its expression increased significantly severity Compared preoperative, declined at 3 months after surgery. = 0.02), bilateral 0.04) grade 0.03) independently associated suggest is useful clinical varicocele, this key deciding early effective treatment protecting fertility patients.