Follow up of intima–media thickness after severe early‐onset preeclampsia

• DOI: 10.1111/aogs.12499
• Publication Date: 2014-09-09T07:39:31Z
• Authors: Judith Blaauw; Esteban T.D. Souwer; Sophie M. Coffeng; Andries J. Smit; Jasper J. van Doo...; Marijke M. Faas; Maria G. van Pampus
• Keywords: Intima-media thickness; Endothelial Dysfunction; Subclinical infection

Early-onset preeclampsia is associated with premature cardiovascular disease. We previously demonstrated that femoral intima-media thickness (IMT) and markers of disease were increased in women 1 year after early-onset preeclampsia. The current study measured (progression of) IMT, risk factors endothelial cell dysfunction 4-5 years postpartum the same women.Case-control study.Formerly preeclamptic women.IMT carotid arteries was by ultrasound, as a marker subclinical atherosclerosis. Various conventional determined, well serum activation inflammation. Values compared those first (preeclamptic) pregnancy.We included 17 formerly (cases) 16 controls. Mean interval between index delivery day investigation 4.7 for cases 4.3 Neither differences nor progression IMT observed Increased blood pressure, body mass index, triglycerides inflammatory found controls.IMT not an almost 5-year history severe indicator risk. This suggests transient adaptive response women. persistence this group emphasizes need long-term follow-up.