Cervical cancer prevention among older women – challenges in screening, diagnostic workup and treatment

• DOI: 10.1111/aogs.14162
• Publication Date: 2021-04-18T18:49:28Z
• Authors: Line W. Gustafson; Lone Kjeld Petersen; Pinar Bor; Berit Andersen; Anne Hammer
• Keywords: high-risk HPV; cervical cancer screening; Uterine Cervical Neoplasms; cervical intraepithelial neoplasia; EXCISION; 03 medical and health sciences; 0302 clinical medicine; Uterine Cervical Neoplasms/prevention & control; Humans; Practice Patterns, Physicians'; human papillomavirus; Aged; RISK; Aged, 80 and over; Vaginal Smears; postmenopausal; colposcopy; Age Factors; Cervical Intraepithelial Neoplasia/prevention & control; Uterine Cervical Dysplasia; 3. Good health; Women's Health Services; INTRAEPITHELIAL NEOPLASIA; Colposcopy; Gynecology; PATTERNS; Female

Cervical cancer incidence and mortality have declined dramatically after screening for cervical was implemented. Yet, studies reported high rates at older age despite low HPV prevalence of precursor lesions. The underlying reason these findings remains unclear. However, it is well known that the impact depends not only on uptake effectiveness but also diagnostic workup (ie colposcopy), treatment follow-up. In women, sensitivity performance colposcopy are impaired due to age-dependent changes cervix. this commentary, we aimed discuss challenges in clinical management identify crucial areas particular interest future research.