Erythrocyte metabolism

• DOI: 10.1111/apha.14081
• Publication Date: 2024-01-25T14:12:42Z
• Authors: Panagiotis N. Cha...; Nikos V. Margarit...; Vassilis Paschalis; Anastasios A. The...; Ioannis S. Vrabas; Antonios Kyparos; Angelo D'Alessandro; Michalis G. Nikol...
• Keywords: Metabolic pathway; Nucleic acid metabolism; Purine metabolism; Carbohydrate Metabolism

Abstract Our aim is to present an updated overview of the erythrocyte metabolism highlighting its richness and complexity. We have manually collected connected available biochemical pathways integrated them into a functional metabolic map. The focus this map on main consisting glycolysis, pentose phosphate pathway, redox metabolism, oxygen purine/nucleoside membrane transport. Other recently emerging are also curated, like methionine salvage glyoxalase system, carnitine lands cycle, as well remnants carboxylic acid metabolism. An additional goal review dynamics providing key numbers used perform basic quantitative analyses. By synthesizing experimental computational data, we conclude that foundations Additionally, can sense levels oxidative stress adjusting mechanics, function. In conclusion, fine‐tuning controls one most important biological processes, is, loading, transport, delivery.