Combined assessment using optical colonoscopy and computed tomographic colonography improves the determination of tumor location and invasion depth

• DOI: 10.1111/ases.12313
• Publication Date: 2016-09-21T05:16:46Z
• Authors: Hidenori Kanazawa; Kenichi Utano; Shigeyoshi Kijima; Takahiro Sasaki; Yasuyuki Miyakura; Hisanaga Horie; Alan Kawarai Lefor; Hideharu Sugimoto
• Keywords: Adult; Male; Colonoscopy; Middle Aged; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Colonic Neoplasms; Preoperative Care; Humans; Female; Neoplasm Invasiveness; Colonography, Computed Tomographic; Aged; Retrospective Studies

AbstractIntroductionAn accurate assessment of the depth of tumor invasion in patients with colon cancer is an important part of the preoperative evaluation. Whether computed tomographic colonography (CTC) or optical colonoscopy (OC) is better to accurately determine tumor location and invasion depth has not been definitively determined. The aim of this study was to determine the diagnostic accuracy of tumor localization and tumor invasion depth of colon cancer by preoperative OC alone or combined with CTC.MethodsStudy participants include 143 patients who underwent both preoperative CTC using automated CO2 insufflation and OC from July 2012 to August 2013.ResultsThe accuracy of tumor localization was significantly better with CTC than with OC (OC, 90%; CTC, 98%; P < 0.05). No tumor in the descending colon was localized accurately via OC alone. The accuracy of tumor invasion depth was better with CTC plus OC than with OC alone (OC, 55%; CTC, 73%; P < 0.05).ConclusionsOC combined with CTC provides a more accurate preoperative determination of tumor localization and invasion depth than OC alone.