A pilot comparison study of four clinician‐rated atopic dermatitis severity scales

• DOI: 10.1111/bjd.13846
• Publication Date: 2015-04-18T14:43:16Z
• Authors: C.Y. Zhao; A.Q.T. Tran; J.P. Lazo‐Dizon; J. Kim; B.S. Daniel; S.S. Venugopal; L.M. Rhodes; M.G. Law; D.F. Murrell
• Keywords: Male; Adolescent; 610; 32 Biomedical and Clinical Sciences; Dermatitis; Dermatology; anzsrc-for: 1103 Clinical Sciences; Severity of Illness Index; Atopic; Dermatitis, Atopic; 03 medical and health sciences; anzsrc-for: 32 Biomedical and Clinical Sciences; 0302 clinical medicine; Humans; Prospective Studies; 3202 Clinical Sciences; Observer Variation; Eczema / Atopic Dermatitis; anzsrc-for: 1112 Oncology and Carcinogenesis; 3. Good health; Quality of Life; Feasibility Studies; anzsrc-for: 3202 Clinical Sciences; Female; Self Report

Background There are multiple severity outcome measures for atopic dermatitis (AD). is a need to compare the reliability of these measures. Objectives To inter-rater and intrarater objective Scoring Atopic Dermatitis (oSCORAD), Eczema Area Severity Index (EASI), Six Area, Sign (SASSAD) Three Item index (TIS); analyse correlation between quality-of-life instruments Patient-Orientated Measurement, Dermatology Life Quality Skindex-29. Methods Twelve patients with AD attended 1-day scoring exercise by five trained dermatology clinicians. Inter-rater were assessed using intraclass coefficient (ICC). Correlation clinician-rated patient-reported was analysed Spearman's rho. Results Regarding reliability, EASI SASSAD showed good reliabilities, ICCs 0·730 [95% confidence interval (CI) 0·500–0·900] 0·680 (95% CI 0·440–0·880), respectively. However, poor TIS oSCORAD, 0·497 0·233–0·785) 0·498 0·234–0·785), Separate body surface area (BSA) component analyses that oSCORAD BSA contributed its variations. excellent 0·886 0·744–0·952) 0·820 (0·614–0·923), respectively, while an ICC 0·720 0·424–0·878). 0·446 0·037–0·730). measures, only demonstrated moderate Skindex-29 (ρ = 0·611, P 0·035). Conclusions highest supporting it as optimal measure.